Chemical Decorations of “MARs” Residents in Orchestrating Eukaryotic Gene Regulation
نویسندگان
چکیده
منابع مشابه
Bioinformatics of Eukaryotic Gene Regulation
Understanding the mechanisms which control gene expression is one of the fundamental problems of molecular biology. Detailed experimental studies of regulation are laborious due to the complex and combinatorial nature of interactions among involved molecules. Therefore, computational techniques are used to suggest candidate mechanisms for further investigation. This thesis presents three method...
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Recent structure determinations of high order complexes of eukaryotic transcription factors bound to DNA have revealed that residues from their DNA-binding domains are involved in protein-protein interactions between distinct factors. Protein-protein interactions between transactivation domains and coactivators have also been characterized in a number of recently determined structures. These st...
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Infectious bursal disease (IBD) is an economically important viral disease of chickens with worldwide distribution which suppresses the immune system of young chickens. VP2 is the major host-protective protein of infectious bursal disease virus (IBDV). The encoding region of VP2 protein was PCR amplified from a plasmid containing a cDNA fragment of large genomic segment of IBDV, strain D78. Thi...
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The regulation of transcriptional elongation and termination is well documented as a means of controlling the expression of prokaryotic genes, and molecular and genetic analysis has yielded a clear understanding of the diverse mechanisms involved (reviewed in Yanofsky, 1988; Spencer and Groudine, 1990; Kerppola and Kane, 1991). It is now evident that the expression of several eukaryotic viral a...
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ژورنال
عنوان ژورنال: Frontiers in Cell and Developmental Biology
سال: 2020
ISSN: 2296-634X
DOI: 10.3389/fcell.2020.602994